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|data5 =  [[Charak Samhita Research, Training and Skill Development Centre]]
|data5 =  [[Charak Samhita Research, Training and Skill Development Centre]]
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==English name==
==English name==
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* '''Vipaka''' (post-digestive effect): Madhura
* '''Vipaka''' (post-digestive effect): Madhura
* '''Dosha Effect''': Primarily balances [[Vata dosha|vata]], secondarily kapha; aggravates pitta in excess.
* '''Dosha Effect''': Primarily balances [[Vata dosha|vata]], secondarily kapha; aggravates pitta in excess.
* '''Classical Actions''': Medhya (intellect promoter), balya (strength), vajikarana (aphrodisiac), rasayana (rejuvenative).<ref name=":0">{{cite book |last1=Sharma |first1=P.V.|title=Charaka Samhita |publisher=Chaukhamba Orientalia |location=Varanasi |year=2014 |isbn=978-8176371432}}</ref>
* '''Classical Actions''': Medhya (intellect promoter), balya (strength), vajikarana (aphrodisiac), rasayana (rejuvenative).<ref name=":0">{{cite book|last1=Sharma|first1=P.V.|title=Charaka Samhita|publisher=Chaukhamba Orientalia|location=Varanasi|year=2014}}</ref>
[[File:Ashwagandha.jpg|thumb|Ashvagandha]]


==Description==
==Description==


A perennial shrub from the [[Solanaceae]] family, native to India, the Middle East, and Africa. It grows 35–75 cm tall with oval leaves, small greenish-yellow flowers, and red-orange berry-like fruits. The name "Ashwagandha" derives from Sanskrit ''ashva'' (horse) and ''gandha'' (smell), referring to the root's horse-like odor and vigor-promoting effects.<ref>{{cite journal |last1=Mirjalili |first1=Mohammad Hossein |last2=Moharramipour |first2=Saman |last3=Hadian |first3=Javad |title=A review on the production of Withania somnifera (Ashwagandha) active principles: Methods and current status |journal=Journal of Medicinal Plants Research |volume=8 |issue=37 |pages=882–900 |doi=10.5897/JMPR2014.5629 |year=2014}}</ref>
A perennial shrub from the Solanaceae family, native to India, the Middle East, and Africa. It grows 35–75 cm tall with oval leaves, small greenish-yellow flowers, and red-orange berry-like fruits. The name "Ashwagandha" derives from Sanskrit ''ashva'' (horse) and ''gandha'' (smell), referring to the root's horse-like odor and vigor-promoting effects.<ref>{{cite journal |last1=Mirjalili |first1=Mohammad Hossein |last2=Moharramipour |first2=Saman |last3=Hadian |first3=Javad |title=A review on the production of Withania somnifera (Ashwagandha) active principles: Methods and current status |journal=Journal of Medicinal Plants Research |volume=8 |issue=37 |pages=882–900 |doi=10.5897/JMPR2014.5629 |year=2014}}</ref>


==Pharmacognosy==
==Pharmacognosy==
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==References==
==References==
{{reflist}}
{{reflist}}
  This article is under development...

Latest revision as of 12:39, 29 August 2026

Ashwagandha (अश्वगंधा) or Ashvagandha; Withania somnifera), also known as Indian ginseng or winter cherry, is a rasayana (rejuvenator) herb in Ayurveda, valued for its adaptogenic, balya (strength-promoting), and nervine properties. Primarily, the root is used for stress management, vitality, immunity, and musculoskeletal health as documented in classical texts like Charaka Samhita and modern clinical studies.[1][2]

Ashwagandha
Section/Chapter Herb database/Ashwagandha
Botanical name(s) Withania somnifera (Linn.)
Contributors Dr.Yogesh S. Deole
Year of publication 2026
Publisher Charak Samhita Research, Training and Skill Development Centre
DOI 10.47468/CSNE.2026.e01.s10.13

English name

Indian ginseng or winter cherry

Synonyms

Ashwagandha, Wajigandha, Varahakarni

Ayurvedic pharmacological properties

  • Rasa (taste): Madhura (sweet), tikta (bitter)
  • Guna (properties): Snigdha (unctuous), guru (heavy to digest)
  • Virya (potency): Ushna (hot)
  • Vipaka (post-digestive effect): Madhura
  • Dosha Effect: Primarily balances vata, secondarily kapha; aggravates pitta in excess.
  • Classical Actions: Medhya (intellect promoter), balya (strength), vajikarana (aphrodisiac), rasayana (rejuvenative).[3]
Ashvagandha

Description

A perennial shrub from the Solanaceae family, native to India, the Middle East, and Africa. It grows 35–75 cm tall with oval leaves, small greenish-yellow flowers, and red-orange berry-like fruits. The name "Ashwagandha" derives from Sanskrit ashva (horse) and gandha (smell), referring to the root's horse-like odor and vigor-promoting effects.[4]

Pharmacognosy

Key phytoconstituents include withanolides (e.g., withaferin A, withanolide D), sitoindosides, withanosides, alkaloids (withanine, somniferine), and steroidal lactones. Roots contain highest concentrations (1.5–5% withanolides).[5]

Clinical Uses

Reference in Charak Samhita and its actions

Herbs and their activities
Sr.no. Reference in Charak Samhita Activity
1 Cha. Sa. Sutra sthana 4/9(2) Brumhaniya mahakashaya
2 Cha. Sa. Sutra sthana 4/9(7) Balya mahakashaya
3 Cha. Sa. Vimana Sthana 8/136 Virechana Dravyani
4 Cha. Sa. Vimana Sthana 8/139 Madhur skandha
5 Cha. Sa. Chikitsa Sthana 2/1/34 Ingredient in Vajikarana Ghrita
6 Cha. Sa. Chikitsa Sthana 13/109 In the treatment of Udara roga (for lepa)
7 Cha. Sa. Chikitsa Sthana 14/50 Dhupan yoga in arsha roga
8 Cha. Sa. Chikitsa Sthana 17/117 Kshara mixed with madhuk ghrit is used in hikka shwasa
9 Cha.Sa.Chikitsa Sthana 18/75 As an ingredient of Dhumapana yoga
10 Cha.Sa.Chikitsa Sthana 21/123 For pradeha prayoga in granthi visarpa
11 Cha.Sa.Chikitsa Sthana 23/70 As an ingredient of Gandha hasti agada
12 Cha.Sa.Chikitsa Sthana 23/80 As an ingredient of Maha -Gandha hasti agada.
13 Cha.Sa.Chikitsa Sthana 23/244 As an ingredient of Amruta ghrita
14 Cha.Sa. Chikitsa Sthana 27/43 As an ingredient of Kushthadi Taila
15 Cha.Sa. Chikitsa Sthana 22/50 As an ingredient of Utsadana Yoga
16 Cha.Sa.Chikitsa Sthana 28/166 As an ingredient of Ashwagandha Taila paka
17 Cha.Sa.Chikitsa Sthana 28/170 As an ingredient of Vrushamuladi taila
18 Cha.Sa.Chikitsa Sthana 28/173 As an ingredient of Mulaka taila
19 Cha.Sa.Chikitsa Sthana 29/73 As an ingredient of Jeevakadi mahasneha
20 Cha.Sa.Chikitsa Sthana 30/260 As a paniya yoga, in the treatment of Stanya dosha

Bhavaprakasha

  • Pacifies Vata-Kapha dosha
  • Alleviates Shwitra (vitiligo)
  • Shotha (oedema)
  • Kshaya (depletion of tissues)
  • Balya (promotes strength)
  • Rasayani (rejuvenating)
  • Atishukrala (increases semen and sperm count)

Neurological

Reduces stress and cortisol levels (300–600 mg root extract daily); improves sleep quality and cognitive function in trials.[6]

Reproductive

Enhances testosterone, semen quality, and libido in men (675 mg root powder daily).[7]

Musculoskeletal

Increases muscle mass and strength (500 mg extract with resistance training).[8]

Formulations and Dosage

Common preparations:

Formulation Dose Anupana (vehicle)
Churna (powder) 3–6 g BID Warm milk/ghee
Ghrita 5–10 g/day As prescribed
Extract capsules 300–600 mg/day Water

Safety

Generally safe (GRAS status); rare GI upset, drowsiness. Contraindicated in hyperthyroidism, pregnancy (uterine stimulant), and nightshade allergy. LD50 >2 g/kg in rodents.[9]

Research

Over 100 clinical trials support adaptogenic effects; NIH-funded studies are ongoing for anxiety and sleep disorders. Withanolides modulate HPA axis, GABA receptors, and inflammation pathways (NF-κB inhibition).[10]

Current availability

Available

External links

Withania Somnifera

IMPPAT Database link

References

  1. Singh, Narendra; Bhalla, M.; de Jager, P.; Gilca, M. (2021). "Rational use of Ashwagandha in Ayurveda (Traditional Indian Medicine) – A systematic analysis of the scientific evidence for its pharmacological activities". Journal of Ethnopharmacology. 273: 113907. PMC PMC8274455Freely accessible Check |pmc= value (help). PMID 33831467 Check |pmid= value (help). doi:10.1016/j.jep.2021.113907. 
  2. Mishra, Laxmi C.; Singh, Betilda B.; Dagenais, Simon (2000). "Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): a review". Alternative Medicine Review. 14 (5): 348–357. PMID 19803596. 
  3. Sharma, P.V. (2014). Charaka Samhita. Varanasi: Chaukhamba Orientalia. 
  4. Mirjalili, Mohammad Hossein; Moharramipour, Saman; Hadian, Javad (2014). "A review on the production of Withania somnifera (Ashwagandha) active principles: Methods and current status". Journal of Medicinal Plants Research. 8 (37): 882–900. doi:10.5897/JMPR2014.5629. 
  5. Kaushik, M.K.; Kaushik, V.K.; Kumar, A. (2021). "Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomarkers, and pharmacokinetics". Journal of Ethnopharmacology. 267: 113451. PMID 33157267 Check |pmid= value (help). doi:10.1016/j.jep.2020.113451. 
  6. Chandrasekhar, K.; Kapoor, J.; Anishetty, S. (2012). "A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults". Indian Journal of Psychological Medicine. 34 (3): 255–262. PMC 3573577Freely accessible. PMID 23439798. doi:10.4103/0253-7176.106022. 
  7. Ambiye, V.R.; Langade, D.; Dongre, S.; Apte, S.; Joshi, K. (2013). "Clinical evaluation of the spermatogenic activity of the root extract of Ashwagandha (Withania somnifera) in oligospermic males: a pilot study". Evidence-Based Complementary and Alternative Medicine. 2013: 571420. PMC 3863556Freely accessible. PMID 24284701. doi:10.1155/2013/571420. 
  8. Wankhede, S.; Langade, D.; Joshi, K.; Thakurdesai, P.A. (2015). "Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial". Journal of the International Society of Sports Nutrition. 12: 23. PMC 4658772Freely accessible. PMID 26009251. doi:10.1186/s12970-015-0104-9. 
  9. "Withania somnifera (Ashwagandha) Monograph". HerbRally. Retrieved 2026-03-16. 
  10. Speers, A.B.; Cabey, K.A.; Souza, M.J.; Spencer, E.A. (2021). "Effects of Withania somnifera (Ashwagandha) on stress and the stress-related neuropsychiatric disorders anxiety, depression, and insomnia". Current Neuropharmacology. 20 (7): 1–17. doi:10.2174/1570159X19666210813150419.