Talk:Ativisha: Difference between revisions

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== Major Phytoconstituents ==

The pharmacological properties of ''Aconitum heterophyllum'' are primarily attributed to its diterpenoid alkaloids, which are concentrated in the root tubers:<ref name="Mathew2023" />

* '''Diterpenoid Alkaloids:''' Atisine,<ref name="Malhotra2014" /><ref name="Jowett1896" /> atidine,<ref name="Jowett1896" /> heteratisine and benzoylheteratisine,~~<ref name="Jacobs1942" />~~ and aconitine (used as the HPLC marker compound for standardisation).<ref name="Prasad2014" /> Heterophylline, heterophylloidine, fischimine and aconine derivatives <sup>[citation needed]</sup>

* '''Diterpenoid Alkaloids:''' Atisine,<ref name="Malhotra2014" /><ref name="Jowett1896" /> atidine,<ref name="Jowett1896" /> heteratisine and benzoylheteratisine, and aconitine (used as the HPLC marker compound for standardisation).<ref name="Prasad2014" /> Heterophylline, heterophylloidine, fischimine and aconine derivatives <sup>[citation needed]</sup>

* '''Lactones & Flavonoids:''' Bitter principles and phenolic compounds contributing to digestive and anti-inflammatory actions

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<ref name="Wani2022">Wani TA, Kaloo ZA, Dangroo NA. ''Aconitum heterophyllum'' Wall. ex Royle: a critically endangered medicinal herb with rich potential for use in medicine. ''J Integr Med''. 2022;20(2):104–113. [https://doi.org/10.1016/j.joim.2021.12.004 doi:10.1016/j.joim.2021.12.004]</ref>

<ref name="Malhotra2014">Malhotra N, Kumar V, Sood H, Singh TR, Chauhan RS. Multiple genes of mevalonate and non-mevalonate pathways contribute to high aconites content in an endangered medicinal herb, ''Aconitum heterophyllum'' Wall. ''Phytochemistry''. 2014;108:26–34. [https://doi.org/10.1016/j.phytochem.2014.08.025 doi:10.1016/j.phytochem.2014.08.025]</ref>

~~<ref name="Jacobs1942">Jacobs WA, Craig LC. The aconite alkaloids. ''J Biol Chem''. 1942;143(3):589–603. [https://doi.org/10.1016/S0021-9258(18)72589-1 doi:10.1016/S0021-9258(18)72589-1]</ref>~~

<ref name="Jowett1896">Jowett HAD. Contributions to our knowledge of the aconite alkaloids. Part XIII. On atisine, the alkaloid of ''Aconitum heterophyllum''. ''J Chem Soc Trans''. 1896;69:1518–1526. [https://doi.org/10.1039/CT8966901518 doi:10.1039/CT8966901518]</ref>

}}

@@ Line 205: / Line 205: @@
 == Major Phytoconstituents ==
 The pharmacological properties of ''Aconitum heterophyllum'' are primarily attributed to its diterpenoid alkaloids, which are concentrated in the root tubers:<ref name="Mathew2023" />
-* '''Diterpenoid Alkaloids:''' Atisine,<ref name="Malhotra2014" /><ref name="Jowett1896" /> atidine,<ref name="Jowett1896" /> heteratisine and benzoylheteratisine,<ref name="Jacobs1942" /> and aconitine (used as the HPLC marker compound for standardisation).<ref name="Prasad2014" /> Heterophylline, heterophylloidine, fischimine and aconine derivatives <sup>[citation needed]</sup>
+* '''Diterpenoid Alkaloids:''' Atisine,<ref name="Malhotra2014" /><ref name="Jowett1896" /> atidine,<ref name="Jowett1896" /> heteratisine and benzoylheteratisine, and aconitine (used as the HPLC marker compound for standardisation).<ref name="Prasad2014" /> Heterophylline, heterophylloidine, fischimine and aconine derivatives <sup>[citation needed]</sup>
 * '''Lactones & Flavonoids:''' Bitter principles and phenolic compounds contributing to digestive and anti-inflammatory actions
@@ Line 260: / Line 260: @@
 <ref name="Wani2022">Wani TA, Kaloo ZA, Dangroo NA. ''Aconitum heterophyllum'' Wall. ex Royle: a critically endangered medicinal herb with rich potential for use in medicine. ''J Integr Med''. 2022;20(2):104&ndash;113. [https://doi.org/10.1016/j.joim.2021.12.004 doi:10.1016/j.joim.2021.12.004]</ref>
 <ref name="Malhotra2014">Malhotra N, Kumar V, Sood H, Singh TR, Chauhan RS. Multiple genes of mevalonate and non-mevalonate pathways contribute to high aconites content in an endangered medicinal herb, ''Aconitum heterophyllum'' Wall. ''Phytochemistry''. 2014;108:26&ndash;34. [https://doi.org/10.1016/j.phytochem.2014.08.025 doi:10.1016/j.phytochem.2014.08.025]</ref>
-<ref name="Jacobs1942">Jacobs WA, Craig LC. The aconite alkaloids. ''J Biol Chem''. 1942;143(3):589&ndash;603. [https://doi.org/10.1016/S0021-9258(18)72589-1 doi:10.1016/S0021-9258(18)72589-1]</ref>
 <ref name="Jowett1896">Jowett HAD. Contributions to our knowledge of the aconite alkaloids. Part XIII. On atisine, the alkaloid of ''Aconitum heterophyllum''. ''J Chem Soc Trans''. 1896;69:1518&ndash;1526. [https://doi.org/10.1039/CT8966901518 doi:10.1039/CT8966901518]</ref>
 }}