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=== Effect of Brahmi Ghrita ===

=== Effect of Brahmi Ghrita ===

In a clinical study on depression, Brahmi ghrita has resulted in moderate improvement for 40% patients of depression and mild improvement for 55% patients, which is statistically significant at 1% level as compared to placebo.<ref>Deole, Yogesh S1,; Chandola, HM2. A Clinical Study on Effect of Brahmi Ghrita on Depression. AYU (An international quarterly journal of research in Ayurveda) 29(4):p 207-214, Oct–Dec 2008.</ref> In experimental animals, Brahmi ghrita showed mild hyperactivity in gross behaviour and dose dependent mild anxiolytic effect in open field behaviour and elevated plus maze test. Dose dependent variation in effect of Brahmi ghrita is observed in behaviour despair test, as it is mild stimulant at lower dose and depressant at higher dose. It showed significant potentiation of L-DOPA activity in comparison to water control, but the effect was insignificant in comparison to ghrita control.<ref>Deole, Yogesh S1,; Ashok, BK2; Shukla, Vinay3; Ravishankar, B4; Chandola, HM5. Psycho-Pharmacological study on Antidepressant and Anxiolytic Effect of Brahmi Ghrita. AYU (An international quarterly journal of research in Ayurveda) 29(2):p 77-83, Apr–Jun 2008.</ref>

In a clinical study on depression, Brahmi ghrita has resulted in moderate improvement for 40% patients of depression and mild improvement for 55% patients, which is statistically significant at 1% level as compared to placebo.<ref>Deole, Yogesh S1,; Chandola, HM2. A Clinical Study on Effect of Brahmi Ghrita on Depression. AYU (An international quarterly journal of research in Ayurveda) 29(4):p 207-214, Oct–Dec 2008.</ref> In experimental animals, Brahmi ghrita showed mild hyperactivity in gross behaviour and dose dependent mild anxiolytic effect in open field behaviour and elevated plus maze test. Dose dependent variation in effect of Brahmi ghrita is observed in behaviour despair test, as it is mild stimulant at lower dose and depressant at higher dose. It showed significant potentiation of L-DOPA activity in comparison to water control, but the effect was insignificant in comparison to ghrita control.<ref>Deole, Yogesh S1,; Ashok, BK2; Shukla, Vinay3; Ravishankar, B4; Chandola, HM5. Psycho-Pharmacological study on Antidepressant and Anxiolytic Effect of Brahmi Ghrita. AYU (An international quarterly journal of research in Ayurveda) 29(2):p 77-83, Apr–Jun 2008.</ref> In another experimental study, Brahmi Ghrita is observed to enhance learning and memory as analogous to standard drug (piracetam) in normal rats.</ref> Yadav, Kapil Deo; Reddy, K. R. C.; Kumar, Vikas1. Beneficial effect of Brahmi Ghrita on learning and memory in normal rat. AYU (An International Quarterly Journal of Research in Ayurveda) 35(3):p 325-329, Jul–Sep 2014. | DOI: 10.4103/0974-8520.153755<ref>

 

=== Related Chapter ===

=== Related Chapter ===